Calcium- and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory response and maintenance of long-term potentiation (LTP).
Mw; 68,000
泳動結果
HEK293 細胞を，Ser/Thr phosphatase 阻害剤のcalyculin A，またはTyr phosphatase 阻害剤のpervanadateで処理した後，PKC zetaのリン酸化状態の変化を
Zn2+-Phos-tag SDS-PAGEで調べています。
